PET receptor occupancy analysis is a type of radiotracer tracer study that measures the change in receptor occupancy of a radiotracer caused by the test drug. The radiotracer defines 100%...
Posted by | April 19, 2021
One of the biggest challenges to doing brain receptor occupancy is the blood brain barrier (BBB). Before the receptor ligand (PET radiotracer) can find the target receptor it has to...
Posted by | April 11, 2021
Therapeutic drugs targeting a wide range of central nervous system (CNS) disorders work by interacting with CNS receptors. Developing those drugs inevitably leads to needing to understand Drug/ Receptor PK/PD...
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Rat Brain CFN BioLaurus has developed multiple PET PK assays in rats. We are experts in the development of CNS PK assays and determination of the in vivo PK profile...