BioLaurus

Your PreClinical Molecular Imaging Specialists - Imaging the Future of Therapeutics

WHY WORK WITH US?

We aren’t just partners, we are “Hybrid Integrators” – working directly with you from beginning to end, involved in your internal processes as much (or as little) as you wish. You decide, and we bring you solutions. We also seamlessly connect you with institutions for your Phase 1 studies.

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MOLECULAR IMAGING SOLUTIONS

Our translational preclinical molecular imaging capabilities range from PET and SPECT to optical and luminescence imaging. Including static and dynamic (4D) imaging. With expertise in a plethora of therapeutic areas – we can provide your study needs.

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DOWNLOADS, VIDEOS, RESOURCES & BLOG

Don’t need imaging? We can be a scientific resource – sharing information, networking, and posting some fun blogs along the way. Want to be interviewed for one of our articles? Just contact us – we would be happy to include you!

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A few things we’re great at

At BioLaurus, we take pride in our expertise and specialization in the niche field of preclinical molecular imaging. And your needs are important to us – not just as a study, but as a scientific partner as well. We strive for excellence across all performance platforms – scientific, relational and budgetary. And we deliver.

MOLECULAR IMAGING

We are in-vivo preclinical molecular imaging specialists. From discovery stage efficacy studies to follow-on safety/tox studies for clinical stage drugs, we have a demonstrated ability to develop innovative studies and assays, harnessing the power of in-vivo quantitative imaging.

Utilizing various modalities from gene expression and bioluminesence, to ultrasound and PET/SPECT (and more) – we offer a wide array of imaging solutions to provide you options which best meet your preclinical study needs.

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STUDY DESIGN SERVICES

We create a unique imaging strategy, research plan, and study design for your specific needs. We then implement in BioLaurus approved and AAALAC accredited vivariums, in parallel with detailed protocol writing, on site monitoring, BioLaurus in-life study technicians, final data analysis and report. ALL of this is performed while working closely with you – to drive your strategies and goals towards successful study outcomes. We become part of YOUR TEAM.

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NON-HUMAN PRIMATE STUDIES

Need NHP? We can provide solutions using various primate species, conducted in registered facilities and in accordance with local and global animal care and treatment guidelines. Specialties include PK/PD and Safety Studies utilizing SPECT or gamma camera imaging, platelet and T-cell radiolabeling, and more.

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ASSAY DEVELOPMENT

BioLaurus is a leader in the development of novel imaging assays and the adaptation of clinical imaging procedures to the preclinical research space. Bringing the power of quantitative in-vivo and longitudinal means getting the question right first, then assembling the technologies which provide you data-rich imaging for your assay.

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Hot Area!
Platelet Sequestration Studies

Several recent BioLaurus studies have focused on platelet sequestration in NHPs – assessing PLT distribution and clearance post-treatment.

3D and 4D Imaging

You can benefit from various static and dynamic imaging modalities which provide you with real-time sequestration data, in video format.

3D and 4D Videos

Check out the SOT Poster!

BioLaurus was part of a Poster presentation with Ionis Pharmaceuticals, at SOT (March 2017), describing liver and splenic clearance of platelets in NHPs, post-treament.

POSTER LINK

Various Species Utilized

Platelet sequestration studies can be performed in various species – most frequently we have seen application in rabbit and NHP for these types of studies.

CASE STUDY

CT Imaging of EBC-1 Lung Metastasis

The evaluation of lung metastases in mouse models has long been challenging. Lung metastasis models such as the EBC-1 non-small cell lung carcinoma that grows along bronchi and blood vessels can be imaged by CT. In images shown here, normal and tumor bearing inflated lungs are imaged in situ at 30um resolution on a SCANCO Medical microCT-40

TECHNOLOGY

Micro-CT Imaging is a 3D solution, offering resolution to 10-30um.

MORPHOLOGY

Lung tissue characteristics create low x-ray attenuation of air – results in high contrast.

CASE STUDY – ASSAY DEVELOPMENT

Novel Enterocyte GI Contrast Agent

We developed a novel CT contrast agent to track in-vivo lipid absorption in the small intestine. This agent allows for real-time assessment of enterocyte function by visualizing the absorption and secretion of free fatty acides from triglycerides in the small intestines of rats.

TECHNOLOGY

Breakthrough technology could measure the rates of lipid absorption and secrtion in-vivo.

ASSAY DEVELOPMENT

BioLaurus is a leader in the development of novel imaging assays.

Client Testimonials

Don’t take our word for it – here’s what our clients say:

The BioLaurus “Can-Do” philosophy, flexibility, and agility with study design changes afforded the opportunity to conduct investigative studies that were not possible with other clinical research organizations.

Husam Younis, PharmD, PhD

Senior Director, Nonclinical Development

Dr Bourdon is a distinguished Bio-imaging expert with extensive experience and knowledge of imaging technologies. With great attention to detail, the study was only performed once, with all goals met – allowing for swift publication.

Jeff (Ssucheng) Hsu, PhD

Director, Immuno-Pharmacology

BioLaurus’ performance was outstanding in the study design and they provided trustworthy and insightful data and creative analysis techniques to get the most information from available data. I look forward to working with them in the future.

David Brewster, PhD, DABT

VP and Global Head – Drug Safety Evaluation

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Latest Blogs

Check out our recent blogs about molecular imaging, preclinical studies, drug development – and plenty of other fun, related topics. If you have a suggestion for a blog (or would like to be interviewed), let us know!

Biolaurus.com new website layout

Biolaurus’ New Website

We are focusing on services and assay development that better align with your projects and the way you work.

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Image 1 schrodingers-cat

Cat got your tongue?

A BioLaurus Blog by Kimberly Brue If you don’t know where your keys, your car, or even your kids are at a certain time – you aren’t alone. Every day[…]

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The evolution of molecular imaging

The Evolution of What?

Since the earth was born and man was created, there has been much evolution in the universe. Man, as a species, has evolved to what we are today (and we[…]

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Let us help you with your molecular imaging challenges.

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