Cynomolgus monkey autologous In-111 PLT biodistribution pre and post drug treatment. Note the large increase in liver sequestration and diminished circulating PLT and spleen concentrations A wide range of drugs...
Imaging Notes is a series of short informational articles for the non-expert to gain insights into the exciting opportunities and practical issues involved in doing molecular imaging studies. Imaging Notes will be updated twice monthly.
Cynomolgus monkey autologous In-111 PLT biodistribution pre and post drug treatment. Note the large increase in liver sequestration and diminished circulating PLT and spleen concentrations A wide range of drugs...
PET receptor occupancy analysis is a type of radiotracer tracer study that measures the change in receptor occupancy of a radiotracer caused by the test drug. The radiotracer defines 100%...
One of the biggest challenges to doing brain receptor occupancy is the blood brain barrier (BBB). Before the receptor ligand (PET radiotracer) can find the target receptor it has to...
Therapeutic drugs targeting a wide range of central nervous system (CNS) disorders work by interacting with CNS receptors. Developing those drugs inevitably leads to needing to understand Drug/ Receptor PK/PD...